SV40, an ingredient found in vaccines is Associated with Causing Different Cancerous Conditions!
Below are types of human cancers in which SV40 has been found. By clicking on the name, you will link to some study abstracts that provides additional details. Please note that this is not a comprehensive list of all SV40-associated cancers or all medical/scientific articles written about the detection of SV40 in cancer.
Anaplastic thyroid carcinomas (ATC)
Huang H., et al. Identification in human brain tumors of DNA sequences specific SV40 large T antigen . Brain Pathol 1999 Jan;9(1):33-42.
Zhen H.N., et al. Expression of the simian virus 40 large tumor antigen (Tag) and formation of Tag-p53 and Tag-pRb complexes in human brain tumors . Cancer 1999 15;86(10):2124-32.
Martini, F., et al. Simian Virus 40 Footprints in Normal Human Tissues, Brain and Bone Tumours of Different Histotypes ; 1997. Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 55-66.
Krieg, P., et al. Episomal simian virus 40 genomes in human brain tumors Proc Natl Acad sci USA 1981 Oct;78(10):6446-50.
Huang H., et al. Identification in human brain tumors of DNA sequences specific SV40 large T antigen . Brain Pathol 1999 Jan;9(1):33-42.
Huang H., et al. Identification in human brain tumors of DNA sequences specific SV40 large T antigen . Brain Pathol 1999 Jan;9(1):33-42.
Zhen H.N., et al. Expression of the simian virus 40 large tumor antigen (Tag) and formation of Tag-p53 and Tag-pRb complexes in human brain tumors . Cancer 1999 15;86(10):2124-32.
Martini, F., et al. Simian Virus 40 Footprints in Normal Human Tissues, Brain and Bone Tumours of Different Histotypes ; 1997. Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 55-66.
Wang, J and Garcea R.L., et al, Simian virus 40 DNA sequences in human brain and bone tumours . Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 13-21.
14 of 17 pediatric brain tumors (13 choroid plexus tumors, 3 ependymomas and 1 ganglioneuroma) were positive for SV40 regulatory region sequences. Butel, J.S., et al. Detection of authentic SV40 DNA sequences in human brain and bone tumors Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 23-32.
Lednicky, et al., Natural simian virus 40 strains are present in human choroid plexus and ependymoma Virology . 1995 Oct 1;212(2):710-7. tumors.
Huang H., et al. Identification in human brain tumors of DNA sequences specific SV40 large T antigen . Brain Pathol 1999 Jan;9(1):33-42.
Zhen H.N., et al. Expression of the simian virus 40 large tumor antigen (Tag) and formation of Tag-p53 and Tag-pRb complexes in human brain tumors . Cancer 1999 15;86(10):2124-32.
Martini, F., et al. Simian Virus 40 Footprints in Normal Human Tissues, Brain and Bone Tumours of Different Histotypes ; 1997. Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 55-66.
Wang, J and Garcea R.L., et al, Simian virus 40 DNA sequences in human brain and bone tumours . Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 13-21.
14 of 17 pediatric brain tumors (13 choroid plexus tumors, 3 ependymomas and 1 ganglioneuroma) were positive for SV40 regulatory region sequences. Butel, J.S., et al. Detection of authentic SV40 DNA sequences in human brain and bone tumors Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 23-32.
Lednicky, et al., Natural simian virus 40 strains are present in human choroid plexus and ependymoma Virology . 1995 Oct 1;212(2):710-7. tumors.
Huang H., et al. Identification in human brain tumors of DNA sequences specific SV40 large T antigen . Brain Pathol 1999 Jan;9(1):33-42.
Huang H., et al. Identification in human brain tumors of DNA sequences specific SV40 large T antigen . Brain Pathol 1999 Jan;9(1):33-42.
Zhen H.N., et al. Expression of the simian virus 40 large tumor antigen (Tag) and formation of Tag-p53 and Tag-pRb complexes in human brain tumors . Cancer 1999 15;86(10):2124-32.
Martini, F., et al. Simian Virus 40 Footprints in Normal Human Tissues, Brain and Bone Tumours of Different Histotypes ; 1997. Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 55-66.
Krieg, P., et al. Episomal simian virus 40 genomes in human brain tumors Proc Natl Acad sci USA 1981 Oct;78(10):6446-50.
Huang H., et al. Identification in human brain tumors of DNA sequences specific SV40 large T antigen . Brain Pathol 1999 Jan;9(1):33-42.
Huang H., et al. Identification in human brain tumors of DNA sequences specific SV40 large T antigen . Brain Pathol 1999 Jan;9(1):33-42.
Zhen H.N., et al. Expression of the simian virus 40 large tumor antigen (Tag) and formation of Tag-p53 and Tag-pRb complexes in human brain tumors . Cancer 1999 15;86(10):2124-32.
Krieg, P., et al. Episomal simian virus 40 genomes in human brain tumors Proc Natl Acad sci USA 1981 Oct;78(10):6446-50.
Zhen H.N., et al. Expression of the simian virus 40 large tumor antigen (Tag) and formation of Tag-p53 and Tag-pRb complexes in human brain tumors . Cancer 1999 15;86(10):2124-32.
Krieg, P., et al. Episomal simian virus 40 genomes in human brain tumors Proc Natl Acad sci USA 1981 Oct;78(10):6446-50.
Huang H., et al. Identification in human brain tumors of DNA sequences specific SV40 large T antigen . Brain Pathol 1999 Jan;9(1):33-42.
Krieg, P., et al. Episomal simian virus 40 genomes in human brain tumors Proc Natl Acad sci USA 1981 Oct;78(10):6446-50.
Zhen H.N., et al. Expression of the simian virus 40 large tumor antigen (Tag) and formation of Tag-p53 and Tag-pRb complexes in human brain tumors . Cancer 1999 15;86(10):2124-32.
Martini, F., et al. Simian Virus 40 Footprints in Normal Human Tissues, Brain and Bone Tumours of Different Histotypes ; 1997. Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 55-66.
Wang, J and Garcea R.L., et al, Simian virus 40 DNA sequences in human brain and bone tumours . Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 13-21.
Martini, F., et al. Simian Virus 40 Footprints in Normal Human Tissues, Brain and Bone Tumours of Different Histotypes ; 1997. Brown F, Lewis AM (eds): Simian Virus 40 (SV40): A Possible Human Polyomavirus. Dev Biol Stand. Basel, Karger, 1998, vol 94, pp 55-66.
Cristaudo A, et al., SV40 enhances the risk of malignant mesothelioma among people exposed to asbestos: a molecular epidemiologic case-control study . Cancer Res. 2005 Apr 15;65(8):3049-52.
Pass HI, et al., Evidence of an important role for SV40 in mesothelioma . Thorac Surg Clin. 2004 Nov;14(4):489-95.
Carbone M, et al., New developments about the association of SV40 with human mesothelioma . Oncogene. 2003 Aug 11;22(33):5173-80.
Butel JS, et al., Association between SV40 and non-Hodgkin’s lymphoma . Leuk Lymphoma. 2003;44 Suppl 3:S33-9.
Vivaldi, et al., Simian virus 40-like sequences from early and late regions in human thyroid tumors of different histotypes . J Clin Endocrinol Metab. 2003 Feb;88(2):892-9.
Anaplastic Thyroid Carcinomas (ATC)
Vivaldi, et al., Simian virus 40-like sequences from early and late regions in human thyroid tumors of different histotypes . J Clin Endocrinol Metab. 2003 Feb;88(2):892-9.
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